SAFE trial


title: Resuscitation Fluids - The SAFE Trial tags: #FFICM notebook: 🌑-FFICM type: inprogress


source: MCQs and SBAs in Intensive Care Medicine (Oxford Higher Special Training)

Fluid and electrolyte therapy

Flashcard type:basic
What did the SAFE trial of 2004 look at? Saline Vs Albumin
What year was the SAFE trial, looking at Saline Vs Albumin? 2004
How many patients were in the SAFE trial, looking at Saline Vs Albumin? ~7000
What did the 2004 SAFE trial show as it's primary findings when comparing Saline to Albumin? No difference in mortality or organ failure at 28 days
What did a retrospective review of the SAFE trial of Saline VS Albumin show that was concerning? Increased mortality at 2yrs for folk with traumatic brain injury and Albumin Resuscitation
Why is albumin resuscitation maybe a bad thing for those with traumatic brain injury? SAFE trial showed increased mortality at 2 years