Stem cell transplant
title: Haemopoetic Stem Cell Transplant tags: #FFICM notebook: 🌑-FFICM type: inprogress
source: mcqs-and-sbas-in-intensive-care-medicine-oxford-higher-special-training
| Flashcard | type:basic |
|---|---|
| What percentage of patients who receive a haemopoeitic stem cell transplant will require critical care? | 13% |
| What percentage of patients who have a haematological malignancy will require critical care? | 7% |
| What are the two main categories of stem cell transplant? | Autologous and Allogenic |
| Where does an autologous stem cell transplant come from? | It comes from yourself |
| Where does an allogenic stem cell transplant come from? | It comes from someone else |
| Which category of stem cell transplants can be subdivided into matched v unmatched and related v unrelated? | Allogenic |
| What are the two main categories of Allogenic stem cell transplant? | Matched V Unmatched Related V Unrelated |
| What is the main advantage of an autologous stem cell transplant? | No graft versus host |
| What is the main disadvantage of an autologous stem cell transplant? | No graft versus disease |
| What is the main disadvantage of an allogenic stem cell transplant? | Risk of graft versus host |
| What is the main advantage of an allogenic stem cell transplant? | Chance of graft versus disease |
| What is the main advantage of a more mismatched allogenic stem cell transplant? | Increased amount of graft versus disease effect |
| What is the main disadvantage of a more mismatched allogenic stem cell transplant? | Increased amount of graft versus host effect |
| If someone post haemopoeitic stem cell transplant presents with skin changes, GI upset, and liver involvement, what should you think of? | Graft Versus Host |
| At what time scale are you most likely to get Graft Versus Host following your stem cell transplant? | A month to two months |
| What are your chances of death if you get severe graft versus host following stem cell transplant? | 75% |