Toxic epidermal necrolysis
title: Toxic Epidermal Necrolysis tags: #FFICM notebook: 🌑-FFICM type: inprogress
source: mcqs-and-sbas-in-intensive-care-medicine-oxford-higher-special-training
| Flashcard | type:basic |
|---|---|
| Is staphylococcal scalded skin due to bacterial toxin or immune reaction? | Bacterial toxin |
| What type of staphs cause scalded skin syndrome? | Minority of staph aureus |
| Is staphylococcal scalded skin more common in adults or children? | Children |
| Which is nastier, stevens-johnson syndrome or toxic epidermal necrolysis? | TEN |
| Which is more benign, stevens-johnson syndrome or toxic epidermal necrolysis? | Stevens-Johnson Syndrome |
| How much of the body surface area is affected if you have Stevens-Johnson syndrome? | Less than 10% |
| What two things do you need to get the diagnosis of toxic epidermal necrolysis? | Clinical Presentation and Biopsy results |
| Is Toxic Epidermal Necrolysis due to bacterial toxin or immune reaction? | Immune Reaction |
| What cells are being targeted by the body in Toxic Epidermal Necrolysis? | Keratinocytes |
| Do you get bullae in Toxic Epidermal Necrolysis? | Yes |
| Do bullae distinguish between Scalded Skin Syndrome, Stevens Johnson, and Toxic Epidermal Necrolysis? | No, they all get bullae |
| What is the main trigger for Toxic Epidermal Necrolysis? | Drugs |
| What is the most common cause for mortality from Toxic Epidermal Necrolysis? | Bacterial Infection resulting in sepsis and multiorgan failure |
| Where should you treat someone with Toxic Epidermal Necrolysis? | In a burns unit |
| How high is the mortality in the most serious forms of Toxic Epidermal Necrolysis? | More than 90% |