Bmj misc

title: Misc BMJ Question Facts tags: #FFICM notebook: ð-FFICM type: inprogress

Flashcard	type:basic
What is the brand name for epoprostenol?	Flolan
What is the brand name for prostacyclin?	Flolan
What is the other generic name for epoprostanol?	Prostacyclin
What is the other generic name for Prostacyclin?	Epoprostanol
What are the two generic names for Flolan?	Epoprostanol and Prostacyclin
How might you use prostacyclin in RRT?	As an "anticoagulant" that inhibits platelets
What part of the clotting cascade does prostacyclin act on?	It inhibits platelets
In the context of pulm hypertension drugs, what is the half life of prostacyclin?	Around 40 seconds
In the context of pulm hypertension drugs, what is the half life of epoprostanol?	Around 40 seconds
In the context of pulm hypertension drugs, what is the half life of flolan?	Around 40 seconds
Does aspirin act temporarily or permenently on platelets?	Permenantly
Does clopidogrel act temporarily or permenently on platelets?	Permenantly
What is paclitaxel used for?	It's the drug in drug eluding stents
What's the class of drug of tirofiban?	It's a glycoprotein IIb/IIIa inhibitor
Is tirofiban given IV or orally in ACS?	IV
Is tirofiban given as an IV bolus or infusion in ACS?	IV infusion
Whilst renal function is allowed to go down a little bit after introducing an ACEi, what is the big pathology you don't want to miss if it goes down by loads?	Renal Artery Stenosis
What is the best compromise way to detect renal artery stenosis (sensitive test without nasty contrast)?	MR Angiography
Whats the best way to detect renal artery stenosis if you aren't fussed about giving nephrotoxic contrast?	Percutaneous Angiography
Are B cells part of the Cell Mediated or Humoral Immune Response?	Humoral
Are T cells part of the Cell Mediated or Humoral Immune Response?	Humoral
What types of chains make up antibodies?	Heavy and Light
How many heavy and light chains are there in each antibody?	Two heavy Two light
How high is the mortality risk in the first three months following PE?	15% +
When using a thermodilution technique for cardiac output measurement, what part of the graph do we look at to assess cardiac output?	Area Under The Curve of Temperature Change
How quickly should you inject cold water in a thermodilution technique?	Less than 4 seconds
Will injecting too little cold water over estimate or underestimate cardiac output?	Over Estimate
In venous drainage of the pharynx, what does the pharyngeal plexus drain into?	The internal jugular vein
In venous drainage of the pharynx, does the pharyngeal plexus drain into the internal jugular vein?	Yes
In venous drainage of the pharynx, does the pharyngeal plexus drain into the external jugular vein?	No
In venous drainage of the pharynx, what structure drains into the internal jugular vein?	The pharyngeal plexus
How many layers are in the pharynx wall?	4
What ratio counts as a low hepatic extraction ratio?	Less than 0.3
What is the genetic inheritance of rapid acetylator status?	Autosomal Dominant
What is the genetic inheritance of slow acetylator status?	Autosomal Recessive
What is the difference in genetic inheritance between rapid and slow acetylator status for drugs?	Rapid is Autosomal Dominant, Slow is Autosomal Recessive
What is the normal value for mixed venous oxygen content (and units)	12-17mL/dl
What equation do you use "Huffner's Constant" in?	Calculating Mixed Venous Oxygen Content
When calculating mixed venous oxygen content, what is the numerical value for Huffners constant?	1.34
Which is more common in causing infective endocarditis? Strep Viridans or Staph Aureus?	Staph Aureus
What is the cardiac arrest dose of adrenaline in children?	10 micro / kg
What curve describes a "first order, single compartment" elimination model?	Negative Exponential Curve
Can you give steroids to treat Guillain Barre?	No! They don't do any good!
In anaphlyaxis, when do mast cell tryptase levels peak?	One to Two Hours
In anaphlyaxis, when do mast cell tryptase levels start to rise?	After 30 minutes
In anaphlyaxis, what is the half life of mast cell tryptase?	Two Hours
In anaphlyaxis, when might mast cell tryptase levels be back to normal?	Within 8 hours
In diabetes management, what is the mechanism of action of alpha glucosidase inhibitors?	Slows down digestion of starch in intestine
In diabetes management, what is the class of drugs that slows down digestion of starch in small intestine?	Alpha glucosidase inhibitors
What is the normal cerebral blood flow, in ml/100g/minute?	Around 50
What is the normal carotid body blood flow, in ml/100g/minute?	Around 2000
In acute bleeding, what do you give cryoprecipitate for?	Increase fibrinogen
In acute bleeding, how do you increase fibrinogen levels?	Give cryoprecipitate
What counts as a VERY low level of fibrinogen in acute bleeding?	Less than 0.5g/L
What counts as a low level of fibrinogen in acute bleeding?	Less than 1g/L
In acute bleeding, what should you target your fibrinogen levels at?	Greater than 1g/L
In acute bleeding, what do you give FFP for?	To bring down APTT/PT
In acute bleeding, how would you bring down APTT or PT?	Give FFP
In acute bleeding, what APTT or PT counts as too high, and should be brought down?	If greater than 1.5x the mean

Now for some cloze questions:

Flashcard	type:cloze
The {{c1::specific heat capacity::term}} of a substance is the amount of {{c2::energy::something}} needed to change the {{c2::temperature::something}} of {{c3::1kg::amount}} of substance by {{c2::1C::amount}}
The {{c1::energy needed to heat an object (E)::term and symbol}} is calculated by the {{c2::mass of the object (m)::term and symbol}} times the {{c3::specific heat capacity of the substance (c)::term and symbol}} times the {{c4::temperature change wanted (Î¸)::term and symbol}}
{{c1::Mixed venous oxygen content (CvO2)::term and symbol}} is the amount of {{c2::oxygen carried by 100ml of mixed venous blood::definition}}
{{c1::Mixed Venous Oxygen Content (CvO2)::term and symbol}} is calculated by ( {{c2::1.34 times haemoglobin (g/dl)::first bit of equation}} times {{c3::mixed venous O2 sats (SvO2) times 0.01::second bit of equation}} ) plus ( {{c4::PaO2 x PvO2::final bit of equation}} )