heparin induced thrombocytyopaenia HIT

title: Heparin Induced Thrombocytopaenia tags: #FFICM notebook: ð-FFICM type: inprogress

source: mcqs-and-sbas-in-intensive-care-medicine-oxford-higher-special-training

Flashcard	type:basic
In Heparin Induced Thrombocytopaenia (HIT), what is the 4 T's HIT Score for?	Likelihood of having HIT
What scoring system works out the likelihood of having heparin induced thrombocytopaenia?	The 4 T's HIT Score
A 4 T's HIT Score of 0-3 means that you	Are unlikely to have HIT
A 4 T's HIT Score of 4 or 5 means that you	Are likely to have HIT
A 4 T's HIT Score of 6,7 or 8 means that you	Are very likely to have HIT
If you stop anticoagulation with heparin for someone you think has HIT, should you start an alternative?	Yes
At what time scale should you give someone warfarin, if you had to stop their heparin because of HIT?	Not before 7 days, as that can make their thrombocytopaenia worse
What are the four components of the 4 T HIT score?	Thrombocytopaenia, Timing of Platelet Fall, Thrombosis, Any Other Cause
In the 4T's scoring system for HIT Likelihood, what is the maximum total score you can get?	8
In the 4T's scoring system for HIT Likelihood, what is the maximum score you can get for a single category?	2
In the 4T's scoring system for HIT, how many points would you get if your platelet count dropped by >50%?	2
In the 4T's scoring system for HIT, how many points would you get if your platelet count dropped by 30-50%?	1
In the 4T's scoring system for HIT, how far do your platelets need to fall to get any points?	At least 30%
In the 4T's scoring system for HIT, how far do your platelets need to fall to get two points?	At least 50%
In the 4T's scoring system for HIT, how far do your platelets need to fall to get one point?	At least 30%
In the 4T's scoring system for HIT, how soon after heparin do your platelets need to fall to get one point?	Within one hundred days
In the 4T's scoring system for HIT, how soon after heparin do your platelets need to fall to get two points?	Within ten days
Is HIT immune mediated or non immune mediated?	Proper HIT (Type 2) is immune mediated
In immune mediated HIT, what is the underlying pathology?	Immune complexes against heparin-platelet factor 4 complex
Why should you care about the existence of the heparin-platelet factor 4 complex?	It's the target of HIT
Is heparin induced thrombocytopenia more common in men or women?	Women

Some cloze stuff:

Flashcard	type:cloze
The four components of the {{c1::4 T's::name of scoring system}} Score to work out if {{c2::someone is likely to have HIT::what is it a scoring system for?}} are: {{c3::Thrombocytopaenia}} {{c4::Timing of Platelet Fall}} {{c5::Thrombosis}} {{c6::Any Other Likely Cause}}