Wed3November0919PM 20

Are the following true or false concerning growth hormone?

True / False

It is anabolic Correct

Most of its effects are mediated via IGF-I Correct

It promotes the growth spurt at puberty Incorrect answer selected

It is lipolytic Correct

It is synthesised by the lactotrophs of the anterior pituitary Correct

Explanation

Growth hormone is synthesised by the somatotrophs of the anterior pituitary and it produces its effects mainly through IGF-1 produced by the liver.

Production is controlled by the hypothalamic secretion of GHRH and somatostatin.

Its effects include:

Anti-insulinic recruitment of glucose

Anabolic effects, and

Lipolysis.

It is also, in conjunction with priming of the anterior pituitary by sex hormones, responsible for the growth spurt during puberty.

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Average score: 72.66%

Times answered: 248