Wed13October0734AM 3

Are the following true or false with regard to cells of the immune system?

True / False

Each B cell lineage produces only one type of antibody at any one time Correct

Antibodies cannot penetrate cells Correct

Antibodies are produced in large quantities by plasma cells (plasmocytes) Correct

B lymphocytes (B cells) are part of the humoral response Correct

Antibodies comprise 2 alpha chains and 2 beta chains Incorrect answer selected

Explanation

B and T lymphocytes are part of the adaptive humoral or specific/adaptive immune response. B lymphocytes (B cells) are produced and mature in the bone marrow while T lymphocytes migrate and mature in the thymus.

After maturation both are released and found in the circulation and peripheral lymphoid organs (for example, spleen, lymph nodes) where they differentiate further after contact with an antigen.

Activated B cells produce plasma cells which are responsible for producing large numbers of specific antibodies according to the lineage of that B cell. However "class switching" is a biological mechanism that changes a B cell's abiltiy to produce immunoglobulin (antibodies) from one type to another, such as from the isotype IgM to the isotype IgG.

Antibodies (IgA, IgG, IgM, etc) comprise two heavy and two light chains.

Antibodies bind to circulating antigens but cannot enter cells.

Reference:

National Institute of Allergy and Infectious Diseases (NIAID). Immune System.

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Average score: 71.90%

Times answered: 237