Wed10November0747AM 10

Are the following true of false of the clinical use of metformin?

True / False

Vitamin A absorption may decrease Correct

Nausea, diarrhoea and abdominal pain may occur Correct

May be used in the management of polycystic ovarian syndrome (PCOS) Correct

Should be avoided if the patients eGFR is less than 30 ml/min/1.73 m2 Correct

Should be withdrawn in those who have had a recent myocardial infarction Correct

Explanation

Metformin is used in type II diabetes and in the management of PCOS (unlicenced). It should not be commenced if the patient's eGFR is less than 30 ml/min/1.73 m2 and it should be withdrawn in acute myocardial infarctions.

Common side effects include abdominal pain, diarrhoea and nausea. Metformin may cause a decrease in vitamin B12 absorption.

Reference:

Medicines Complete. Metformin Hydrochloride.

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Average score: 75.23%

Times answered: 239