Tue16November0750PM 8

Which of the following is correct regarding the syndrome of inappropriate antidiuretic hormone secretion (SIADH)?

(Please select 1 option)

Typically associated with a serum osmolality of 295-315 mosm/kg (normal range 278-305)

A cause of dependent oedema

Treated with furosemide

Typically associated with squamous cell bronchial carcinoma

A complication of carbamazepine treatment Correct

Explanation

SIADH is associated with:

Drugs, (e.g. carbamazepine)

Selective serotonin reuptake inhibitors (SSRIs)

Head injury

Tumours

Pneumonia, and typically with

Oat cell (rather than squamous cell) lung cancer.

SIADH may respond to demeclocycline (not furosemide).

It produces a euvolaemic hyponatraemia, and dependent oedema is not a feature (if present, it makes the diagnosis less likely).

Plasma osmolality is low and urine sodium and osmolality are high.

Answer Statistics

1

6%

2

5%

3

2%

4

37%

5

52%

Times answered: 269