Thu7October1232PM 7

Are the following true or false of glycolysis?

True / False

Does not consume oxygen Incorrect answer selected

Occurs within the cytoplasm of the cell Correct

Involves the conversion of lactate to pyruvate Correct

Acetyl co-enzyme A is the main cofactor Incorrect answer selected

Has a net gain of 9 molecules of ATP for every molecule of glucose consumed Correct

Explanation

Acetyl co-enzyme A is involved in the citric acid cycle rather than glycolysis.

Glycolysis is the process in which glucose is broken down to pyruvate. For each molecule of glucose it consumes 2 molecules of ATP and generates 4. Therefore, there is a net gain of 2 ATP molecules per molecule of glucose.

During anaerobic metabolism pyruvate is reduced to lactate (not lactate to pyruvate) to regenerate NAD+ and allow glycolysis to continue.

Glycolysis takes place in the cytoplasm and does not consume oxygen or produce carbon dioxide.

Reference:

Power I, Kam P (eds.) Principles of Physiology for the Anaesthetist. 2nd edn. London: Hodder Arnold; 2008.

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