Thu7October1232PM 5

Are the following true or false of the circulation?

True / False

Blood flow to the liver is about 25% of the cardiac output Incorrect answer selected

Normal global cerebral blood flow is 250 ml/100g/minute Correct

Normal blood flow to the carotid bodies exceeds 1000 ml/100g/minute Correct

Coronary blood flow is autoregulated Correct

Cerebral perfusion pressure in adults is normally 30-40 mmHg Correct

Explanation

The normal cerebral blood flow is 54 ml/100g/minute.

The carotid bodies have the highest blood flow per unit weight of any organ in the body. This enables them readily to detect falls in PaO2.

Organ Blood Flow

(ml/minute/100g)

Hepatoportal 58

Kidney 420

Skin 13

Skeletal muscle 2.7

Heart 87

Carotid body 2000

Thyroid gland 560

Cerebral perfusion pressure (CPP) = mean arterial pressure (MAP) - intracranial pressure (ICP).

Typical values are: MAP = 90 mmHg and ICP = 12.

Normal CPP ranges between 75-85 mmHg.

Although the liver constitutes 2.5% of total body weight it receives almost 25% of the cardiac output.

The liver has a dual blood supply:

Hepatic artery 500 ml/min (100 mmHg), 95% oxygen saturation

Portal vein 1000 ml/min (7 mmHg), 70% oxygen saturation.

The coronary, renal and cerebral circulations are capable of autoregulation.

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Average score: 69.87%

Times answered: 231