Thu18November0253AM 9

True / False

Is used in treatment of both supraventricular and ventricular arrhythmias Correct

May be associated with pulmonary fibrosis Correct

Is highly protein bound Correct

Is a class II antiarrhythmic according to the Vaughan-Williams classification Incorrect answer selected

Is a benzofuran derivative Correct

Explanation

Amiodarone is a benzofuran derivative and is a class III antiarrhythmic but also has class I, II and IV activity. It is used in both supraventricular and ventricular arrhythmias.

Oral bioavailability is between 50-70% and it is highly protein bound at around 97%.

Side effects associated with long term use include pulmonary fibrosis, thyroid dysfunction and peripheral neuropathy.

Reference:

Peck TE, Hill SA, Williams M. Pharmacology for Anaesthesia and Intensive Care. 3rd ed. Edinburgh: Cambridge University Press; 2008.

Sasada M, Smith S. Drugs in Anaesthesia & Intensive Care. 3rd ed. New York: Oxford University Press; 2010.

Answer Statistics

Not enough data to display the statistics

Average score: 81.96%

Times answered: 275