Sun28November0440PM 37

True / False

Release is inhibited by angiotensin II Correct

Is synthesised in the zona glomerulosa of the adrenal cortex Correct

Is a mineralocorticoid Correct

Is synthesised from cholesterol Incorrect answer selected

Decreases sodium reabsorption and potassium excretion Incorrect answer selected

Explanation

Aldosterone is a mineralocorticoid synthesized from cholesterol in the zona glomerulosa of the adrenal cortex. Its main stimulus for release is angiotensin II.

Reduced tubular perfusion and sodium concentration and ECF volume leads to an increase in renin release from the kidney. This in turn converts angiotensinogen to angiotensin I. Angiotensin converting enzyme converts angiotensin I to angiotensin II.

Angiotensin II is a potent vasoconstrictor but also stimulates aldosterone release. Aldosterone in turn promotes sodium and water reabsorption and potassium excretion.

Answer Statistics

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Average score: 81.77%

Times answered: 249