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True / False

May interact with monoamine oxidase inhibitors Correct

Acts on both alpha and beta adrenergic receptors Correct

Is used to treat narcolepsy Correct

Is not available orally Correct

Has direct and indirect actions Correct

Explanation

Ephedrine has both direct and indirect actions on alpha- and beta-adrenergic receptors. It also inhibits monoamine oxidase (MAO) and may interact with other MAO inhibitors, precipitating a hypertensive crisis.

Ephedrine is commonly used to treat hypotension but other indications include nasal congestion, nocturnal enuresis and narcolepsy and it can be given orally or intramuscularly.

Reference:

Peck TE, Hill SA, Williams M. Pharmacology for Anaesthesia and Intensive Care. 3rd ed. Edinburgh: Cambridge University Press; 2008.

Sasada M, Smith S. Drugs in Anaesthesia & Intensive Care. 3rd ed. New York: Oxford University Press; 2010.

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Average score: 74.29%

Times answered: 245