Sun21November0452PM 8

Is it true or false that the following are prodrugs?

True / False

Enalapril Correct

Parecoxib Correct

Codeine Correct

Diamorphine Correct

Captopril Incorrect answer selected

Explanation

A prodrug is a drug with no inherent activity that becomes converted to its active form when metabolised.

Examples include:

Enalapril (to enalaprilat)

Diamorphine (to 6-monoatcylmorphine)

Codeine (to morphine), and

Parecoxib (to valdecoxib).

Reference:

Peck TE, Hill SA, Williams M. Pharmacology for Anaesthesia and Intensive Care. 3rd ed. Edinburgh: Cambridge University Press; 2008.

Answer Statistics

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Average score: 61.86%

Times answered: 258