Sun14November1246PM 36

In the management of overdose:

True / False

Ethylene glycol causes metabolic acidosis Correct

Repeated oral activated charcoal is beneficial in carbamazepine overdose Incorrect answer selected

Theophylline can cause hyperkalaemia Correct

Cocaine overdose causes metabolic acidosis Correct

N-acetylcysteine decreases mortality in encephalopathy associated with paracetamol overdose Correct

Explanation

Cocaine overdose causes:

a metabolic acidosis

tachycardia

hypertension

dilated pupils

hypertonia

convulsions, and

coma.

Ethylene glycol causes metabolic acidosis 30 minutes to 12 hours post ingestion. Additional features include an ethanol like inebriation, acidosis, and calcium oxaluria. At 12 to 36 hours patients may develop pulmonary oedema, cyanosis, and death is most common in this phase. Renal failure may occur at 2 to 3 days.

N-acetylcysteine decreases mortality in encephalopathy associated with paracetamol overdose.

Repeated use of oral activated charcoal is beneficial in an overdose of:

carbamazepine

aspirin

dapsone

paraquat

phenobarbitone

quinine, and

theophylline.

Hypokalaemia is associated with theophylline overdose (not hyperkalaemia).

Answer Statistics

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Average score: 65.28%

Times answered: 265