Sat27November0556PM 36

Are the following true or false of iron deficiency anaemia?

True / False

Results in an increase in 2,3 DPG levels Incorrect answer selected

May result in a decreased mixed venous oxygen saturation Incorrect answer selected

Decreases blood viscosity Correct

Is associated with high ferritin levels Correct

Is typically associated with a high reticulocyte count Correct

Explanation

A reduction in haemoglobin results in reduced oxygen delivery to tissues. Compensatory mechanisms include increased oxygen extraction that may cause a decreased mixed venous oxygen saturation.

Blood viscosity is reduced and 2,3 DPG levels increase which reduces the affinity of haemoglobin for oxygen.

The reticulocyte count is a measure of the numbers of immature red blood cells derived from the marrow. Is is typically raised when there is high red cell turnover such as chronic haemorrhage and haemolytic anaemia. It is not a feature of iron deficiency anaemia but the reticulocyte count may increase following iron therapy.

Reference:

Hans GA, Jones N. Preoperative anaemia. Contin Educ Anaesth Crit Care Pain. 2013;13:71-74.

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