Sat27November0445PM 32

True / False

May cause emergence phenomena Correct

Is an imidazole ester Correct

Induces anaesthesia within one arm-brain circulation Correct

Is an antagonist at the NMDA receptor Correct

Is given by the intravenous route only Correct

Explanation

Ketamine is a phenylcyclidine derivative. The onset of action is longer than one arm-brain circulation. It is a non-competitive antagonist at the NMDA receptor.

It causes dissociative anaesthesia and may cause emergence phenomena such as unpleasant dreams and hallucinations.

It may be administered by the intravenous, intramuscular and oral routes.

Reference:

Peck TE, Hill SA, Williams M. Pharmacology for Anaesthesia and Intensive Care. 3rd ed. Edinburgh: Cambridge University Press; 2008.

Sasada M, Smith S. Drugs in Anaesthesia & Intensive Care. 3rd ed. New York: Oxford University Press; 2010.

Answer Statistics

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Average score: 76.22%

Times answered: 249