Sat27November0445PM 23
Regarding the pharmacological control of phaeochromocytoma, are the following alpha-adrenergic receptor antagonists?
True / False
Nifedipine Correct
Phentolamine Correct
Atenolol Correct
Propranolol Correct
Phenoxybenzamine Correct
Explanation
Alpha-adrenergic receptor blockade is particularly important in the treatment of phaeochromocytoma and should be started before beta blockers.
Alpha blockers include phenoxybenzamine, phentolamine, prazosin and doxazosin. Generally phenoxybenzamine is preferred as this provides irreversible blockade.
Atenolol and propranolol are both beta-adrenergic receptor antagonists, and nifedipine is a calcium antagonist.
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