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title: Refeeding tags: #FFICM #Medicine #Nutrition notebook: 🌑-FFICM


source: [[eLfH]] category: [[nutrition]]

Nutrition in critical care

Refeeding

This is a condition occuring after restarting nutrition after starvation. 1

Cells increase their uptake of phosphate resulting in:

  • Severe serum hypophosphataemia
  • Hypokalaemia
  • Hypomagnasaemia 1

In a metanalysis, 34% of patients on ICU experienced hypophosphataemia after feeding was restarted. 2

Risk Factors:

  • Post Op
  • Chronic Malnutrition/Malabsorption (IBD/Pancreatitis/Short Bowel/CF/Marasmus)
  • Morbid Obese with Profound Weight Loss
  • "High Stress" patients unfed for 7+ days
  • Prolonged Fasting
  • Chronic Alcoholism
  • Oncology 2

NICE Criteria for at-risk groups is2:

One Or More Of Two Or More Of
BMI <16 BMI <18.5
Weight Loss > 15% in last 6 Months Weight Loss > 10% last 6 months
Little nutritional intake past 10 days Little nutritional intake past 5 days
Low K, Phos, Mg before feeding History of alcohol/drugs/medications putting at risk*
  • Insulin, Chemo, Antacids, Diuretics

Flashcard type:basic
How low does your BMI need to be at very high risk of refeeding? Less than 16
How low does your BMI need to be at high risk of refeeding? Less than 18
How long do you need to have been starved from to be at very high risk of refeeding? 10 days plus
How long do you need to have been starved from to be at high risk of refeeding? 5 days plus
How high should amount of feed be, to reduce the risk of refeeding in those who had been starved? ~50% of energy requirements
How long should you be on a reduced amount of feed after starving, if attempting to avoid risk of refeeding? 5 days

Cloze

Flashcard type:cloze
NICE Classify those at very high risk of refeeding as people with:
{{c1::BMI less than 16}}
{{c2::Starvation for more than 10 days}}
{{c3::Weight Loss of 15%+}}
{{c4::Electrolyte Derangement}}
The classic derangement of electrolytes in refeeding syndrome would be low {{c1::phosphate}}, {{c1::potassium}}, and {{c1::magnesium}}
In patients who have been starved, you should give {{c1::thiamine}} before feeding to reduce the risk of {{c2::Wernicke's encephalopathy}}

Clinically that will show as:

  • Confusion
  • Delirium
  • Seizures
  • Respiratory Failure
  • Rhabdomyolysis
  • CV Collapse 1

It can precipitate Wernicke's encephalopathy, so thiamine should be given before feeding restarts. 2

You can prevent it using a restricted calorie intake over the first few days. 1

The trial of this reduced 60 day mortality and reduced resp infections. 1

Plus some more questions from [[mcqs-and-sbas-in-intensive-care-medicine-oxford-higher-special-training]]

Flashcard type:basic
Does malabsorption increase your risk of refeeding syndrome? Yes
Does alcoholism increase your risk of refeeding syndrome? Yes
Does diabetes increase your risk of refeeding syndrome? Yes
Does being elderly increase your risk of refeeding syndrome? Yes
Does PPI use increase your risk of refeeding syndrome? No
Does renal failure increase your risk of refeeding syndrome? No
Does anorexia increase your risk of refeeding syndrome? Yes
Does malignancy increase your risk of refeeding syndrome? Yes
Does malignancy increase your risk of refeeding syndrome? Yes
Does diuretic use increase your risk of refeeding syndrome? Yes - Electrolyte Mess up
Does antacid use increase your risk of refeeding syndrome? Yes - Chelated Phospate

Sources


  1. Nutrition in critical care. R. Chowdhury and S. Lobaz. BJA Education, 19(3): 90e95 (2019) 

  2. Refeeding Syndrome. eLFH - ACUMEN - The Acute Medicine Network.